Picture of Nubain


What is Nubain?

It is an analgesic or pain-relieving medication that belongs to the Phenanthrene series. It is known by the generic name Nalbuphine and brand name Nubain.

Nubain Uses

The medicine is used for the prevention and treatment of pain that ranges from mild to severe in intensity. It may be administered to patients during childbirth and before and after surgery. It can also be used by a doctor for various other reasons.

Nubain Mechanism of Action

The drug works as an analgesic. It blocks a few receptor spots in the Central Nervous System (CNS), which helps reduce painful sensations.

Who Should Not Use Nubain?

The drug should not be used by individuals who have a history of allergy to any ingredient in the medication or any other opoid analgesic (such as Hydromorphine or Morphine) of the same variety. Those taking Sodium Oxybate (GHB) should also avoid this drug.

Picture of Nubain

Picture 1 - Nubain

The medicine should also be avoided by:

  • Those suffering from Diarrhea, due to poisoning
  • Those depending on any substance or medication
  • A particular type of bowel disorder, known as Pseudomembranous colitis

Nubain Usage Instructions

Those taking the drug should have it as per the directions of their physician. Check the label for exact instructions about the dosage. Do not use it in higher amount or more frequently than recommended by your doctor. Otherwise, you may form a habit of this drug.

Do not take the medication if you find the vial (in which the drug is contained) damaged or cracked in any way. You should also avoid its usage if you find foreign particles inside the vial or find the medicine discolored.

Keep the drug, including the needles and the syringes, out of the reach of children. It is safe not to reuse syringes, needles or other items. Properly dispose of all the products. If you are unsure about the local regulations for proper disposal of these materials, get in touch with your pharmacist, nurse or doctor for assistance.

Sometimes, the drug is used as an injection at home. Consult a healthcare provider for proper information and guidance before using the medicine. Ask about proper administration of the medication through injections.

Nubain Missed Dose

If you miss a dose of this drug, take it as soon as you remember. However, you should skip the dose if it is about time for you to take the next dosage. Follow your regular dose and do not take extra amounts of this medication to make up for the lost dose. Never use two doses at one time.

Nubain Overdose

In case an overdose is suspected, patients or their family members should call an emergency medical care facility, the local poison control center or contact 1-800-222-1222 to get in touch with the American Association of Poison Control Center.

How to Store Nubain?

The medicine is generally stored and handled by experienced health care providers. In case you are using the drug at home, you should store it as recommended by your health care provider or pharmacist. You should store it away from pets or children in your home.

Nubain Precautions

Certain precautions must be maintained while taking this drug:

  • Do not operate machines or drive cars while taking this medicine. The drug leads to side effects like blurred vision, drowsiness or dizziness. Taking this drug, either alone or along with alcohol, might reduce your ability to perform tasks with all your faculties intact.
  • Those who have undergone Gastrointestinal Tract Surgery and have a history of alcohol or substance abuse should also refrain from using the medicine.

Image of Nubain

Picture 2 - Nubain Image

Do not use the drug if you are suffering from any of the following problems:

  • High blood pressure
  • Asthma or other breathing disorders
  • Kidney disorders
  • Underactive thyroid
  • Liver ailments
  • Problems in urination
  • Acute inflammatory bowel disease
  • Cardiac problems
  • Depression or other mental problems
  • Prostate problems
  • Heart attack, along with nausea and vomiting

Nubain and Pregnancy

Inform your doctor if you are pregnant, planning for pregnancy or breastfeeding if you have been prescribed this medicine. Intake of this medication might affect your pregnancy and also cause harm to your fetus. Also inform him or her whether you are taking any dietary supplement, herbal preparation or any other prescription or non-prescription drug.

Nubain and Medicinal Interactions

Nubain may interact with certain drugs, such as:


It can reduce the effectiveness of Nubain.


Its effectuality may be lowered due to the usage of this medication.

Side effects like drowsiness or labored respiration may also arise due to interactions with a few other drugs, such as:

  • Barbiturate anesthetics (like Thiopental)
  • Cimetidine
  • Sodium oxybate (GHB)
  • Phenothiazines (like Promethazine)
  • Narcotic analgesics (like Fentanyl)

Nubain Side Effects

Although the majority of users of this drug do not suffer from any problems, a few individuals are found to experience a number of side effects of this medication. These include:

Mild side effects

The mild symptoms arising due to the usage of the medicine include:

  • Drowsiness
  • Dizziness
  • Constipation
  • Dry mouth
  • Headache
  • Whirling sensation
  • Nausea
  • Vomiting
  • Clammy skin, due to sweating

Severe side effects

These involve health problems that are more acute in nature, such as:

  • Chest pain
  • Fainting
  • Difficulty in urinating
  • Dizziness
  • Vomiting
  • Numbness of an arm or leg
  • Severe headache
  • Seizures
  • Changes in vision
  • Retarded heartbeat

Affected individuals may also suffer from severe allergic reactions. These include health issues like rashes, hives, difficulty in breathing, tightness in the chest and inflammation of the face, mouth, tongue or lips.

If any of these severe symptoms arise, medical attention should be sought immediately. Get in touch with your doctor or call 911 to seek urgent medical remedy.

The list of side effects is not a comprehensive one. Consult your healthcare provider to know about all the possible problems that you may experience due to the usage of the drug.






Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <strike> <strong>